C Peptide and insulin do not influence plasma semicarbazide-sensitive amine oxidase activity
نویسندگان
چکیده
منابع مشابه
Inhibition of bovine plasma semicarbazide-sensitive amine oxidase by caffeine.
Semicarbazide-sensitive amine oxidase (SSAO) is a copper-containing enzyme that catalyzes the oxidative deamination of endogenous and exogenous primary amines. SSAO exists in mammals both as a plasma-soluble and as a membrane-bound form, and its active site is able to come into contact with numerous xenobiotic, amine-containing compounds. The kinetic studies performed in this work showed that c...
متن کاملSemicarbazide-sensitive amine oxidase and kidney disease.
With better understanding of the molecular mechanisms underpinning chronic kidney disease, the roles of inflammation and fibrosis are becoming increasingly inseparable. The progression of renal disease is characterized by pathomorphological changes that consist of early inflammatory responses followed by tubulointerstitial fibrosis, tubular atrophy, and glomerular and vascular sclerosis. Curren...
متن کاملOrigins of serum semicarbazide-sensitive amine oxidase.
Semicarbazide-sensitive amine oxidases (SSAO) are enzymes that are capable of deaminating primary amines to produce aldehyde, ammonia, and hydrogen peroxide. This activity has been associated with vascular adhesion protein-1 (VAP-1) and is found in the serum, endothelium, adipose, and smooth muscle of mammals. Circulating SSAO activity is increased in congestive heart failure, diabetes, and inf...
متن کاملAnti-inflammatory effects of inhibiting the amine oxidase activity of semicarbazide-sensitive amine oxidase.
Human semicarbazide-sensitive amine oxidase (SSAO) or vascular adhesion protein-1 (VAP-1) is a copper-containing amine oxidase (AOC3, EC 1.4.3.6) that has both enzymatic and adhesive function. SSAO catalyzes the oxidative deamination of primary amines, resulting in the formation of the corresponding aldehyde and release of hydrogen peroxide and ammonia. Membrane-bound SSAO is an inflammation-in...
متن کاملSemicarbazide-sensitive amine oxidase and mortality in chronic heart failure.
effects of beta(1)and beta(2)-adrenergic receptors on cardiac myocyte apoptosis: role of a pertussis toxin-sensitive G protein. Circulation 1999; 100: 2210–2. [13] Börjesson M, Magnusson Y, Hjalmarson Ar , Andersson B. A novel polymorphism in the gene coding for the beta1adrenergic receptor associated with survival in patients with heart failure. Eur Heart J 2000; 21: 1853–8. [14] Schafer AJ, H...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 2001
ISSN: 0012-186X,1432-0428
DOI: 10.1007/s001250051632